Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
KIRC | rs4404473 | chr3:48353626 | A/G | 4.6E-5 | 513 | 39.62 | 41.27 | 19.13 | KM Plot |
KIRC | rs4443465 | chr5:111168282 | A/C | 5.04E-5 | 525 | 40.28 | 37.53 | 21.82 | KM Plot |
KIRC | rs4461012 | chr15:56133376 | A/T | 3.05E-10 | 515 | 2.3 | 39.17 | 39.23 | KM Plot |
KIRC | rs4495228 | chr5:111168283 | A/C | 5.04E-5 | 525 | 40.28 | 37.53 | 21.82 | KM Plot |
KIRC | rs4511915 | chr3:48343858 | G/A | 3.14E-5 | 521 | 39.62 | 40.93 | 19.13 | KM Plot |
KIRC | rs4511916 | chr3:48350366 | G/A | 3.27E-5 | 523 | 39.62 | 41.27 | 19.13 | KM Plot |
KIRC | rs452547 | chr21:46020311 | G/A | 3.06E-5 | 517 | 16.37 | 34.87 | 42.27 | KM Plot |
KIRC | rs4541174 | chr19:56164716 | C/T | 1.79E-6 | 510 | 41.87 | 37.67 | 7.4 | KM Plot |
KIRC | rs4596531 | chr6:2400921 | G/A | 3.33E-9 | 520 | 39.85 | 40.57 | 12.07 | KM Plot |
KIRC | rs4709910 | chr6:165375403 | C/T | 3.31E-5 | 519 | 15.83 | 44.23 | 39.38 | KM Plot |
KIRC | rs4712473 | chr6:20280762 | C/T | 1.07E-8 | 521 | 9.02 | 35.83 | 43.68 | KM Plot |
KIRC | rs4724620 | chr7:47790912 | T/C | 7.37E-5 | 525 | 24.57 | 39.17 | 40.3 | KM Plot |
KIRC | rs4801803 | chr19:37966923 | A/G | 3.08E-5 | 527 | 21.82 | 45.47 | 38.97 | KM Plot |
KIRC | rs4819263 | chr21:47950866 | G/A | 1.78E-5 | 519 | 39.08 | 43.25 | 6.87 | KM Plot |
KIRC | rs4845444 | chr1:152530125 | G/A | 5.85E-5 | 525 | 35.6 | 44.05 | 37.77 | KM Plot |